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Illustrative vial: FOXO4FOXO4

Illustrative presentation

INFORMATIONAL REFERENCE

FOXO4

FOXO4-related research explores cellular senescence and cell-survival signaling. The protein FOXO4 and the engineered peptide FOXO4-DRI are different entities; confirming identity is essential before interpreting potential applications.

Research focus & potential applications

Cellular senescence
Cell-survival pathways

What the research shows

Explore the selected studies, their findings and their limits.

Read the findings & sourcesIdentity or formulation distinction

FOXO4 is a transcription-factor protein. A separate engineered peptide, FOXO4-DRI, was studied for disrupting FOXO4–p53 interactions and eliminating senescent cells in laboratory and mouse experiments. A catalog entry named only FOXO4 cannot be assumed to contain FOXO4-DRI. Those experiments do not demonstrate human rejuvenation or identify the material represented here.

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Editorial review: September 23, 2026