Ara-290

ARA-290, or cibinetide, is investigated for tissue-protective signaling and symptoms associated with small-fiber neuropathy. Early human findings suggest a potential role in specific neuropathy settings, with larger studies needed to establish durable outcomes.

Research focus & potential applications

Small-fiber biology

Tissue-protective signaling

What the research shows

Explore the selected studies, their findings and their limits.

Read the findings & sources

Human study discussed

A small randomized pilot enrolled 22 people with sarcoidosis and symptoms of small-fiber neuropathy. ARA-290, also called cibinetide, was associated with improvement in a neuropathy symptom score over four weeks. This was an exploratory, condition-specific study; it cannot establish broad nerve regeneration or durable relief across other causes of neuropathy.

Full study · PMC3563705

For more information, contact info@aurevixpeptides.com.

Editorial review: September 23, 2026